A Case of Small Cell Carcinoma Originated from Sphenoid Sinus in Patient with Recurrent Pituitary Tumor

Small cell carcinoma (SmCC) is a type of neuroendocrine tumor commonly originating in the lung, with only about 2-4% of cases arising at extrapulmonary sites. Extrapulmonary SmCC of the head and neck has a poor prognosis and a high rate of distant metastasis. The paranasal sinus is a rare location for extrapulmonary SmCC and only a few related papers have been published to date. We report a rare case of SmCC originating from the sphenoid sinus in a patient with a recurrent pituitary tumor with a literature review.

A Case of Small Cell Carcinoma Originated from Sphenoid Sinus in Patient with Recurrent Pituitary Tumor

Small cell carcinoma (SmCC) is a type of neuroendocrine tumor commonly originating in the lung, with only about 2-4% of cases arising at extrapulmonary sites. Extrapulmonary SmCC of the head and neck has a poor prognosis and a high rate of distant metastasis. The paranasal sinus is a rare location for extrapulmonary SmCC and only a few related papers have been published to date. We report a rare case of SmCC originating from the sphenoid sinus in a patient with a recurrent pituitary tumor with a literature review.

A Child who has Nasal Polyposis Combined with Bronchiectasis

Nasal polyps are inflammatory lesions of sinonasal tissue that are associated with chronic rhinosinusitis, allergic reaction, and other diseases. Although it is the most common cause of nasal polyps, chronic inflammation of the nasal cavity is not common in children. When nasal polyps are found in childhood, it is important to investigate the cause, such as immunodeficiency disease, cystic fibrosis, primary ciliary dyskinesia, and other syndromes such as Woakes’ syndrome. We report a child who presented with nasal polyps combined with bronchiectasis with a review of related literature.

Clinical Characteristics of Patients Diagnosed with Odontogenic Maxillary Sinusitis through the Consultation with Dentistry / 대한이비인후과학회지

Background and Objectives@#For maxillary sinus diseases, it is not easily determined whether it is of the sinus or dental origin as the root of a tooth is located in the maxillary sinus; hence the need to find the pathologic origin for better clinical results. The purpose of this study was to define the characteristics of patients who had needed to consult both a dentist and an otolaryngologist with respect to the diagnosis and management.Subjects and Method Thirty-one patients who visited the department of dentistry and ENT between 2014 and 2018 were included in the study. Patients with dental implant sinusitis were excluded. We restrospectively reviewed the medical records for chief complaints, assessment, diagnose, treatment, and prognosis of the patients. @*Results@#Of 31 patients, 13 patients were diagnosed with odontogenic rhinosinusitis (ORS), 5 with postoperative cheek cyst (POCC), 2 with radicular cyst without ORS, 7 with sinusitis, and 4 with other diseases. Thirteen patients underwent combined operation and 5 at each department. Follow-up periods was about 6.5 months. There was no disease recurrence except one patients with POCC. @*Conclusion@#There needs to be an active consultation with the dentistry department in case of unilateral sinusitis and past history of dental treatment temporally or when patients show positive findings in CT.

A Case of Head and Neck Mucosa-Associated Lymphoid Tissue Lymphoma Presenting as Progressive Multiple Cranial Nerve Palsy / 대한이비인후과학회지

Lymphoma is a malignant tumor arising from the lymphoid tissue. Chronic inflammation can make lymphocyte accumulation and proliferation in the mucous membrane. Sustained accumulation of these persistent changes in the lymphoid tissues may be responsible for the development of mucosa-associated lymphoid tissue (MALT) lymphoma. Although multiple cranial nerve palsy have been reported in various lymphoma, it has never been reported in MALT lymphoma. A 39-year-old man reported of facial palsy and subsequent vocal fold palsy. MALT lymphoma was diagnosed as involving the parotid gland, nasopharynx, and the skull base. Vocal palsy and facial palsy were successfully recovered after chemotherapy.

Current Status of Pediatric Minimal Invasive Surgery (MIS) in Korea

Minimal invasive surgery (MIS) has rapidly gained acceptance for the management of a wide variety of pediatric diseases. The evolution of minimally invasive surgery (MIS) in children, especially newborns, has been delayed because of the limited working space and unique physiology. With the development of smaller instruments and advanced surgical skills, many of the initial obstacles have been overcome. MIS in children has been used in specialized centers with excellent results, and its application in Korea has been increasing recently. Obvious advantages include better cosmoses, less trauma, and better postoperative musculoskeletal function, especially after thoracic procedures. However, prospective randomized trials and high-level evidence of the benefits of MIS are still scarce. Questions to be answered in the upcoming years will therefore include identify both advantages and potential disadvantages of MIS, especially in neonates. In this review, recent surveys regarding use of MIS by the Korean Association of Pediatric Surgeons were also discussed.

Feasibility and Safety of Laparoscopic Surgery for Obese Korean Women with Endometrial Cancer: Long-Term Results at a Single Institution

The purpose of this study was to evaluate the surgical feasibility of and survival outcome after laparoscopy in obese Korean women with endometrial cancer which has recently been increasing. We reviewed the medical records of the patients treated at our medical institution between 1999 and 2012. The patients were divided into three groups, non-obese (Body Mass Index [BMI] or =28.0). These patient groups were compared in terms of their clinical characteristics, treatment methods, as well as surgical and survival outcomes. In total, 55 of the 278 eligible patients were obese women. There were no differences in the three groups in terms of the proportion of patients who underwent lymphadenectomy, their cancer stage, histologic type, type of adjuvant treatment administered, intra-, post-operative, and long-term complications, operative time, number of removed lymph nodes, blood loss, and duration of hospitalization (P=0.067, 0.435, 0.757, 0.739, 0.458, 0.173, 0.076, 0.124, 0.770, 0.739, and 0.831, respectively). The Disease-Free Survival (DFS) times were 139.1 vs. 121.6 vs. 135.5 months (P=0.313), and the Overall Survival (OS) times were 145.2 vs. 124.8 vs. 139.5 months (P=0.436) for each group, respectively. Obese women with endometrial cancer can, therefore, be as safely managed using laparoscopy as women with normal BMIs.

Pediatric Adrenal Cortical Neoplasm with Histologic Malignancy: A Case Report with Review of Literature

Adrenal cortical neoplasm, especially carcinoma, is extremely rare in pediatric patients. We describe here a rare pediatric case of adrenal cortical neoplasm. A 2-year-old girl presented with an enlarged clitoris. The other physical findings and laboratory tests were nonspecific. The magnetic resonance imaging showed a 4 cm-sized heterogeneously enhancing soft tissue mass with calcification in the left adrenal gland. The mass was removed by laparoscopic operation. Grossly, several fragments of reddish tan soft tissue were present, and they weighed 19 gm in total. Microscopically, there were capsular invasion, diffuse/solid growth pattern with focal necrosis, high cellularity, cytoplasmic eosinophilia, marked nuclear pleomorphism, high N/C ratio, prominent nucleoli, atypical mitotic figures and calcifications, which all suggested adrenal cortical neoplasm of histologic malignancy. On immunohistochemistrical staining, there were positive reactivities to pancytokeratin, cytokeratin 7/20, CEA, inhibin and p53. The Ki-67 labeling index was about 6%. All these findings were indicative of adrenal cortical neoplasm of histologic malignancy.